(R)-Prunasin 是 DNA 聚合酶 β 的抑制剂；。
| Cas No. | 99-18-3 |
| 别名 | 野黑樱苷 |
| Canonical SMILES | O[C@H]1[C@H](O)[C@@H](CO)O[C@@H](O[C@@H](C#N)C2=CC=CC=C2)[C@@H]1O |
| 分子式 | C14H17NO6 |
| 分子量 | 295.3 |
| 溶解度 | DMF: 15 mg/ml,DMSO: 10 mg/ml,Ethanol: 10 mg/ml,PBS (pH 7.2): 5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (R)-Prunasin is a cyanogenic glucoside that is the precursor to amygdalin, a bitter component found in species of the genera Prunus and Olinia. It can be degraded to hydrogen cyanide, glucose, and benzaldehyde by the action of prunasin hydrolase and mandelonitrile lyase and possesses inhibitory effects on plant growth. (R)-Prunasin reportedly inhibits rat DNA polymerase β, which performs base excision repair required for DNA maintenance and replication, with an IC50 value of 98 µM. |
