11(α)-Methoxysaikosaponin F 是一种从柴胡 (ZYCH) 中分离的三萜皂苷 (triterpenoid saponin)，对肝星状细胞-T6 (HSCs-T6) 的 IC50 为 387.7 nM。三萜皂苷具有众多靶标，重要的网络位置和强烈的抑制活性作用，是一种有前景的肝纤维化治疗药物。
| Cas No. | 104109-37-7 |
| 别名 | 11 α-甲氧基柴胡皂苷 F |
| 分子式 | C49H82O18 |
| 分子量 | 959.16 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 11(α)-Methoxysaikosaponin F is a triterpenoid saponin isolated from Bupleurum marginatum Wall.ex DC(ZYCH) which is a promising therapeutic for liver fibrosis. 11(α)-Methoxysaikosaponin F has an IC50 of 387.7 nM with viability of hepatic stellate cells-T6 (HSCs-T6). Triterpenoid saponins have numerous targets, important network positions, and strong inhibitory activity[1]. [1]. Liu X, et al. Bupleurum marginatum Wall.ex DC in Liver Fibrosis: Pharmacological Evaluation, Differential Proteomics, and Network Pharmacology. Front Pharmacol. 2018 May 17;9:524. |
