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2-Di-1-ASP
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
2-Di-1-ASP图片
CAS NO:2156-29-8

2-Di-1-ASP (Compound 18a) 是一种单苯乙烯基染料，广泛用作双链 DNA 的线粒体染色和凹槽结合荧光探针。2-Di-1-ASP 对 G-四链体 (G4) 和双链 DNA 具有选择性。
Cas No.2156-29-8
别名2-[4-(二甲基氨基)苯乙烯基]-1-甲基吡啶碘化物
Canonical SMILESC[N+]1=CC=CC=C1/C=C/C2=CC=C(N(C)C)C=C2.[I-]
分子式C16H19IN2
分子量366.24
溶解度DMSO: 25 mg/mL (68.26 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

2-Di-1-ASP (Compound 18a) is a mono-stryryl dye, and widely used as mitochondrial stain and groove-binding fluorescent probes for double-stranded DNA. 2-Di-1-ASP is selective for G-quadruplex (G4) and double-stranded DNA[1].

2-Di-1-ASP (Compound 18a) displays significant fluorescence enhancements in the presence of G-quadruplex (G4) structures (up to 300-fold), and good selectivity with respect to double-stranded DNA. 2-Di-1-ASP shows fluorimetric selectivity for parallel G4-DNA forms (c-kit2, c-kit87up, c-myc)[1].

[1]. Xie X, et al. Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries. Beilstein J Org Chem. 2019 Aug 6;15:1872-1889.

 
 
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