ADAMTS-5-IN-3 (Example 37-2) 是 ADAMTS-5 和 ADAMTS-4 的有效抑制剂，IC50 分别为 8 和 12 nM。ADAMTS-5-IN-3可用于软骨退化或软骨稳态破坏相关疾病的研究，特别是骨关节病和/或类风湿性关节炎。
| Cas No. | 2688733-96-0 |
| 分子式 | C20H23Cl2N3O3 |
| 分子量 | 424.32 |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | ADAMTS-5-IN-3 (Example 37-2) is a potent inhibitor ofADAMTS-5andADAMTS-4withIC50s of 8 and 12 nM, respectively. ADAMTS-5-IN-3 can be used for the research of diseases involving degradation of cartilage or disruption of cartilage homeostasis, in particular osteoarthrosis and/or rheumatoid arthritis[1]. |
