Calcifediol-d3 是 Calcifediol 的氘代物。Calcifediol 是维生素 D3 的主要循环代谢物,是一种有效的 VDR 抑制剂。
Cas No. | 140710-94-7 |
别名 | 25-羟基维生素D3-[D3],25-hydroxy Vitamin D3-d3 |
分子式 | C27H41D3O2 |
分子量 | 403.66 |
储存条件 | 4°C, protect from light, stored under nitrogen |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Calcifediol-d3 is a deuterium labeled Calcifediol. Calcifediol, a major circulating metabolite of vitamin D3, is a potent VDR inhibitor[1][2]. [1]. Castoldi A, et al. Calcifediol-loaded liposomes for local treatment of pulmonary bacterial infections. Eur J Pharm Biopharm. 2016 Nov 22. [2]. Wei Zheng, et al. Vitamin D-induced vitamin D receptor expression induces tamoxifen sensitivity in MCF-7 stem cells via suppression of Wnt/β-catenin signaling. Biosci Rep. 2018 Dec 7;38(6):BSR20180595. |