GSK 9311 hydrochloride 是 GSK6853 活性较低的类似物，可用作阴性对照。 GSK 9311 hydrochloride 抑制 BRPF 溴结构域，对 BRPF1 和 BRPF2 的 pIC50 值分别为 6.0 和 4.3。
| Cas No. | 2253733-09-2 |
| Canonical SMILES | COC1=C(C(N(CC)C2=C(N3CCNC[C@H]3C)C=C4N(C(N(C4=C2)C)=O)C)=O)C=CC=C1.Cl |
| 分子式 | C24H31N5O3.HCl |
| 分子量 | 474 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Negative control for GSK 6853 Bamborough et al (2016) GSK6853, a chemical probe for inhibition of the BRPF1 bromodomain. ACS Med.Chem.Lett. 7 552 PMID:27326325 |
