| CAS NO: | 1906920-28-2 |
| 包装 | 价格(元) |
| 500μg | 询价 |
| 1mg | 询价 |
| 5mg | 询价 |
| 10mg | 询价 |
| Cas No. | 1906920-28-2 |
| Canonical SMILES | ClC1=C(Cl)C=CC(C2=NN(/C(NC3=CC=CC(OC(F)F)=C3)=N\C#N)C[C@H]2N(C(CO)=O)CC)=C1 |
| 分子式 | C22H20Cl2F2N6O3 |
| 分子量 | 525.3 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (R)-BAY-598 is an inhibitor of the lysine N-methyltransferase SMYD2 (IC50 = 1.7 μM) and a less active enantiomer of (S)-BAY-598 .1 It is selective for SMYD2 over proteinase-activated receptor 1 (PAR1; IC50 = >30 μM). |1. Eggert, E., Hillig, R.C., Koehr, S., et al. Discovery and characterization of a highly potent and selective aminopyrazoline-based in vivo probe (BAY-598) for the protein lysine methyltransferase SMYD2. J. Med. Chem. 59(10), 4578-4600 (2016). |
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