PI3Kδ-IN-2 (YY-20394) 是 PI3Kδ 的强效、口服生物利用度和选择性抑制剂;提取自专利WO 2015055071 A1,化合物10; IC50 为 6.4 nM。
Cas No. | 1702816-75-8 |
别名 | YY-20394 |
Canonical SMILES | CS(=O)(NC1=CC(C2=C3C=C(F)C=C(CN4CCC(C(C)(O)C)CC4)C3=NC(N5CCOCC5)=N2)=CN=C1OC)=O |
分子式 | C28H37FN6O5S |
分子量 | 588.69 |
溶解度 | DMSO : 25 mg/mL (42.47 mM) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | PI3Kδ-IN-2 is a potent and selective inhibitor of PI3Kδ extracted from patent WO 2015055071 A1, compound 10; has an IC50 of 6.4 nM. [1]. WO 2015055071 A1 |