Nilofabicin是一种 FabI 抑制剂。Nilofabicin 对金黄色葡萄球菌的 MIC(90) 为0.5 microg/ml，比利奈唑胺或万古霉素更有效。
| Cas No. | 934628-27-0 |
| 别名 | CG-400549 |
| 分子式 | C19H20N2O2S |
| 分子量 | 340.44 |
| 溶解度 | DMSO : 100 mg/mL (293.74 mM; Need ultrasonic) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Nilofabicin is an enoyl-(acyl-carrier protein) reductase (FabI) inhibitor. Nilofabicin had an MIC(90) of 0.5 microg/ml for Staphylococcus aureus strains and was more potent than either linezolid or vancomycin[1]. [1]. Jong Hwa Yum,et, al. In Vitro Activities of CG400549, a Novel FabI Inhibitor, against Recently Isolated Clinical Staphylococcal Strains in Korea. Antimicrob Agents Chemother. 2007 Jul; 51(7): 2591-2593. |
