Chelerythrine 是一种天然生物碱,是一种有效的选择性 Ca2+/磷脂依赖性 PKC 拮抗剂,IC50 为 0.7 μM。
Cas No. | 34316-15-9 |
别名 | 白屈菜红碱 |
化学名 | 1,2-dimethoxy-12-methyl-[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;chloride |
Canonical SMILES | C[N+]1=C2C(=C3C=CC(=C(C3=C1)OC)OC)C=CC4=CC5=C(C=C42)OCO5.[Cl-] |
分子式 | C21H18ClNO4 |
分子量 | 383.83 |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Chelerythrine affects translocation of PKC from cytosol to plasma membrane. Shown to prevent neurite growth. Induces apoptosis in a concentration- and schedule-dependent manner. |