Asperfuran 是一种由米曲霉菌株生产的抗真菌二氢苯并呋喃衍生物。
| Cas No. | 129277-10-7 |
| Canonical SMILES | OC1=CC(O)=C2C(C[C@H](/C=C/C=C/C)O2)=C1 |
| 分子式 | C13H14O3 |
| 分子量 | 218.3 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Asperfuran is a fungal metabolite originally isolated from A. oryzae that has antifungal and anticancer activities.1 It inhibits the growth of 23 fungi in a disc assay when used at a concentration of 50 μg per disc. Asperfuran inhibits chitin synthase with an IC50 value of 300 μM. It inhibits proliferation of HeLa S3 and L1210 cancer cells (IC50s = 25 μg/ml for both). |1. Pfefferle, W., Anke, H., Bross, M., et al. Asperfuran, a novel antifungal metabolite from Aspergillus oryzae. J. Antibiot. (Tokyo) 43(6), 648-654 (1990). |
