硫酸雌酮是一种无生物活性的雌激素，是一种主要的循环血浆雌激素，可通过类固醇硫酸酯酶 (STS) 转化为具有生物活性的雌激素雌酮 (E1)。硫酸钠可用于乳腺癌的研究。
| Cas No. | 438-67-5 |
| 别名 | 雌酮3-硫酸钠,17β-Estrone 3-sulfate |
| 化学名 | 3-(sulfooxy)-estra-1,3,5(10)-trien-17-one, monosodium salt |
| Canonical SMILES | O=C1CC[C@@]2([H])[C@]3([H])CCC4=CC(OS([O-])(=O)=O)=CC=C4[C@@]3([H])CC[C@@]21C.[Na+] |
| 分子式 | C18H21O5S•Na |
| 分子量 | 372.4 |
| 溶解度 | 2mg/mL in ethanol 30mg/mL in DMSO, or in DMF |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Estrone 3-sulfate is an endogenous steroid and an estrogen ester that is biologically inactive. It is converted by steroid sulfatase into estrone . Estrone 3-sulfate has been investigated as a ligand for targeting organic anion transporting polypeptides for the detection of hormone-dependent breast cancers.[1] Reference:
[1]. Banerjee, N., Fonge, H., Mikahil, A., et al. Estrone-3-sulphate, a potential novel ligand for targeting breast cancers. PLoS One 8(5), (2013). |
