Rebamipide mofetil是 Rebamipide (OPC12759)的口服活性前药。Rebamipide是一种粘膜保护剂。Rebamipide诱导COX-2表达,增加 PGE2 水平,并以 COX-2 依赖的方式增强胃黏膜防御。
Cas No. | 1527495-76-6 |
分子式 | C25H26ClN3O5 |
分子量 | 483.94 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Rebamipide mofetil is an orally active prodrug of Rebamipide (OPC12759). Rebamipide is a mucoprotective agent. Rebamipide induces COX-2 expression, increases PGE2 levels, and enhances gastric mucosal defense in a COX-2-dependent manner[1]. [1]. Cho, Eui Hwan, et al.Pharmaceutical composition comprising rebamipide precursor for oral administration for preventing or treating immune disease and metabolic disease.WO2017138717A1. |