(Rac)-PF-06256142 是 PF-06256142 的较弱的对映体。(Rac)-PF-06256142 是 D1 受体 (D1 receptor) 的激动剂，其 EC50 值为 107 nM。(Rac)-PF-06256142 可用于精神分裂症和帕金森病的研究。
| Cas No. | 1609580-97-3 |
| 分子式 | C21H16N4O2 |
| 分子量 | 356.38 |
| 溶解度 | DMSO : 25 mg/mL (70.15 mM; Need ultrasonic) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (Rac)-PF-06256142 is the less effective enantiomer of PF-06256142 . (Rac)-PF-06256142 is an agonist of D1 receptor, with an EC50 of 107 nM. (Rac)-PF-06256142 can be used for the research of schizophrenia and Parkinson’s disease[1]. [1]. Davoren JE, et al. Discovery and Lead Optimization of Atropisomer D1 Agonists with Reduced Desensitization. J Med Chem. 2018 Nov 15. |
