(Rac)-MEM 是 MEM 1003 的外消旋体。MEM1003 是一种二氢吡啶化合物，是有效的 L 型 Ca2+ 通道拮抗剂，具有用于阿尔茨海默氏病研究的潜力。
| Cas No. | 165187-25-7 |
| Canonical SMILES | O=C(OCCOC)C1=C(NC(C)=C(C1C2=CC=CC(C#N)=C2Cl)C(OC(C)C)=O)C |
| 分子式 | C22H25ClN2O5 |
| 分子量 | 432.9 |
| 溶解度 | DMSO : 125 mg/mL (288.75 mM; ultrasonic and warming and heat to 80буC) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | (Rac)-MEM 1003 is the racemate of MEM 1003. MEM 1003, a dihydropyridine compound, is a potent L-type Ca2+ channel antagonist and has the potential for Alzheimer's disease research[1]. References:
[1]. Gregory M Rose, et al. Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73. |
