TRPV3 74a 是一种有效的选择性 TRPV3 拮抗剂。
Cas No. | 1432051-63-2 |
Canonical SMILES | C[C@]1(C[C@@]([C@@H](C2=CC=CC=N2)O)(C3=CC(C(F)(F)F)=CC=N3)C1)O |
分子式 | C17H17F3N2O2 |
分子量 | 338.32 |
溶解度 | DMSO|33.83|100| |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Selective TRPV3 antagonist (KB = 0.56 μM). Displays no significant activity against a panel of other ion channels. Exhibits efficacy in animal models of neuropathic pain. Brain penetrant. |