A caged neurotransmitter used with photolysis
| Cas No. | 2226362-29-2 |
| Canonical SMILES | COC1=C2C(N(C(CC[C@H](N)C(O)=O)=O)CC2)=C([N+]([O-])=O)C=C1.FC(F)(C(O)=O)F |
| 分子式 | C14H17N3O6.CF3COOH |
| 分子量 | 437.3 |
| 溶解度 | Ethanol: 0.25 mg/mL,PBS (pH 7.2): 5 mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations).1Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds.1This compound can be used to investigate the mechanisms of fast synaptic glutamate receptorsin situ. 1.Canepari, M., Nelson, L., Papageorgiou, G., et al.Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmittersJ.Neurosci.Methods112(1)29-42(2001) |
