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NSC 15364
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
NSC 15364图片
CAS NO:4550-72-5
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NSC15364是一种VDAC1寡聚化和细胞凋亡(apoptosis)抑制剂。
Cas No.4550-72-5
别名1,3-二(4-氨基苯基)脲
Canonical SMILESO=C(NC1=CC=C(N)C=C1)NC2=CC=C(N)C=C2
分子式C13H14N4O
分子量242.28
溶解度DMSO: 125 mg/mL (515.93 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

NSC 15364 is an inhibitor of VDAC1 oligomerization and apoptosis[1].

Mitochondrial membrane protein voltage-dependent anion channel 1 (VDAC1) oligomerization represents a prime target for agents designed to modulate apoptosis[1].

[1]. Ben-Hail D, et al. Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction. J Biol Chem. 2016 Nov 25;291(48):24986-25003.

 
 
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