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Propargyl-PEG3-phosphonic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Propargyl-PEG3-phosphonic acid图片
CAS NO:1714139-62-4
包装:250mg
市场价:6789元

Propargyl-PEG3-phosphonic acid 是一种 PROTAC linker,属于 PEG 类。Propargyl-PEG3-phosphonic acid 可用于合成一系列 PROTAC 分子。
Cas No.1714139-62-4
分子式C9H17O6P
分子量252.2
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Propargyl-PEG3-phosphonic acid is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Thorsten Heidelberg, et al. Oligo-ethylene glycol based phosphonate surface modification reagents and use thereof. WO2015065168A1.

 
 
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