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3-Methylcytidine(methosulfate)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
3-Methylcytidine(methosulfate)图片
CAS NO:21028-20-6
包装与价格:
包装价格(元)
10mg询价
25mg询价
50mg询价

3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC.

Cas No.21028-20-6
别名3-甲基胞苷甲基硫酸酯
化学名3-methyl-cytidine, mono(methyl sulfate) salt
Canonical SMILESO=C(N(C)C(C=C1)=N)N1[C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2.O=S(O)(OC)=O
分子式C10H15N3O5.CH4SO4
分子量369.3
溶解度30mg/mL in DMSO, 30mg/mL in DMF
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-Methylcytidine (methosulfate) is a cytidine derivative used as an internal standard for HPLC. 3-Methylcytidine is a common epigenetic modification in tRNA but its role in the cell has not been defined.[1] 3-Methylcytidine has been investigated as a potential biomarker for cancer and was significantly elevated in the urine of breast cancer patients.[2]

Reference:
[1]. D'Silva, S., Haider, S.J., and Phizicky, E.M. A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. RNA 17(6), 1100-1110 (2011).
[2]. Hsu, W.Y., Chen, C.J., Huang, Y.C., et al. Urinary nucleosides as biomarkers of breast, colon, lung, and gastric cancer in Taiwanese. PLoS One 8(12), 1-8 (2013).

 
 
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