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4'-Acetyl Chrysomycin A
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
4'-Acetyl Chrysomycin A图片
包装与价格：
包装价格(元)
1mg询价
5mg询价

A bacterial metabolite with antibacterial and anticancer activities
Canonical SMILESCC(O[C@H]1[C@@H](C)O[C@@H](C(C2=C3OC(C4=CC(C=C)=CC(OC)=C4C3=CC(OC)=C52)=O)=CC=C5O)[C@H](O)[C@]1(C)O)=O
分子式C29H30O10
分子量538.5
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS. aureus(MRSA) and vancomycin-resistant strains ofE. faecalisandE. faecium(MICs = 0.5-2 µg/ml for all). 4'-Acetyl chrysomycin A is cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 0.085-0.26 and 3.4-16 ng/ml, respectively).

1.Wada, S.-I., Sawa, R., Iwanami, F., et al.Structures and biological activities of novel 4'-acetylated analogs of chrysomycins A and BJ. Antibiot. (Tokyo)70(11)1078-1082(2017)

 
 
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