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5,7,8-Trimethoxyflavone
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5,7,8-Trimethoxyflavone图片
CAS NO:23050-38-6
包装:5mg
市场价:1620元

5,7,8-Trimethoxyflavone(Norwogonin5,7,8-trimethylether)来自于穿心莲,可以抑制NO,IC50为39.1μM。5,7,8-Trimethoxyflavone具有抗炎活性。
Cas No.23050-38-6
别名5,7,8-三甲氧基黄酮,Norwogonin 5,7,8-trimethyl ether
Canonical SMILESO=C1C=C(C2=CC=CC=C2)OC3=C(OC)C(OC)=CC(OC)=C13
分子式C18H16O5
分子量312.32
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether), isolated from Andrographis echioides, inhibits NO with an IC50 of 39.1 μM. 5,7,8-Trimethoxyflavone has anti-inflammatory activity[1].

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether; 8, 16, 32, 64 μM; for 24 hours) decreases NO production in a dose-dependent manner in RAW 264.7 macrophages. 5,7,8-Trimethoxyflavone does not change lipopolysaccharide (LPS)-induced (100 ng/mL) cell viability[1].

[1]. De-Yang Shen, et al. Chemical constituents from Andrographis echioides and their anti-inflammatory activity. Int J Mol Sci. 2012 Dec 27;14(1):496-514.

 
 
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