ELOVL1-IN-3 (Compound 22) 是一种有效且具有口服活性的超长链脂肪酸 1 (ELOVL1) 酶延长抑制剂。ELOVL1-IN-3 是研究肾上腺脑白质营养不良 (ALD) 的有用工具。
Cas No. | 2761063-99-2 |
分子式 | C21H23N5O2 |
分子量 | 377.44 |
溶解度 | DMSO : 100 mg/mL (264.94 mM; Need ultrasonic) |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | ELOVL1-IN-3 (Compound 22) is a potent and orally active inhibitor of elongation of very long chain fatty acid 1 (ELOVL1) enzyme. ELOVL1-IN-3 serves as a useful tool for researching adrenoleukodystrophy (ALD)[1]. [1]. Boyd MJ, et al. Discovery of Novel, Orally Bioavailable Pyrimidine Ether-Based Inhibitors of ELOVL1. J Med Chem. 2021;64(24):17777-17794. |