EN523 是 OTUB1 招募者。EN523 靶向 K48 泛素特异性去泛素酶 OTUB1 中的非催化变构半胱氨酸 C23。
| Cas No. | 2094893-05-5 |
| 分子式 | C12H14N2O3 |
| 分子量 | 234.25 |
| 溶解度 | DMSO : 250 mg/mL (1067.24 mM; Need ultrasonic) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | EN523 is a OTUB1 recruiter. EN523 targets a non-catalytic allosteric cysteine C23 in the K48-ubiquitin-specific deubiquitinase OTUB1[1]. [1]. Henning NJ, et al. Deubiquitinase-targeting chimeras for targeted protein stabilization. Nat Chem Biol. 2022;18(4):412-421. |
