Aβ42-IN-2 是一种 γ-secretase 调节剂，详细信息请参考专利文献 WO2016070107 中 的化合物 36。Aβ42-IN-2 对 αβ42 作用的 IC50 值为 6.5 nM 。Aβ42-IN-2 可用于阿尔茨海默症的研究。
| Cas No. | 1914989-80-2 |
| 分子式 | C24H26N6O2 |
| 分子量 | 430.5 |
| 溶解度 | DMSO : 20 mg/mL (46.46 mM; Need ultrasonic) |
| 储存条件 | 4°C, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Aβ42-IN-2 is a γ-secretase modulator extracted from patent WO2016070107, compound example 36. Aβ42-IN-2 has an IC50 of 6.5 nM for αβ42. Aβ42-IN-2 can be used for the research of Alzheimer’s disease[1]. [1]. Steven L. Wagner, et al. Potent gamma-secretase modulators. WO2016070107A1. |
