Veratridine (3-Veratroylveracevine) is naturally occuring steroidal alkaloid found in plants of the lily family, specifically the genera Veratrum and Schoenocaulon. Upon absorption through the skin or mucous membranes, it acts as a neurotoxin by binding to and preventing the inactivation of voltage-gated sodium ion channels in heart, nerve, and skeletal muscle cell membranes. Veratridine increases nerve excitability and intracellular Ca2+ concentrations. Veratridine is a sodium channel agonist that inhibits the peak current of Nav1.7, with an IC50 of 18.39 μM.

纯度：≥98%

CAS：71-62-5