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3′-deoxy Thymidine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3′-deoxy Thymidine图片
CAS NO:3416-05-5
包装与价格：
包装价格(元)
25mg询价
50mg询价
100mg询价
250mg询价

An antiviral nucleoside analog
Cas No.3416-05-5
别名2',3'-二脱氧胸苷
Canonical SMILES[H][C@@]1(N2C(NC(C(C)=C2)=O)=O)O[C@H](CO)CC1
分子式C10H14N2O4
分子量226.2
溶解度DMF: 25 mg/ml,DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml,DMSO: 20 mg/ml
储存条件-20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3′-deoxy Thymidine is a nucleoside analog of thymidine that has antiviral activity.1It inhibits HIV replication in infected human peripheral blood mononuclear cells (PBMCs; EC50= 0.17 µM).23′-deoxy Thymidine (1, 3, 10, or 30 µM) reduces viral plaque formation in CV-1 cells infected with herpes simplex virus 1 (HSV-1).1

1.Waqar, M.A., Evans, M.J., Manly, K.F., et al.Effects of 2’,3’-dideoxynucleosides on mammalian cells and virusesJ. Cell. Physiol.121(2)402-408(1984) 2.Lin, T.-S., Schinazi, R.F., and Prusoff, W.H.Potent and selective in vitro activity of 3’-deoxythymidin-2’-ene (3’-deoxy-2’,3’-didehydrothymidine) against human immunodeficiency virusBiochem. Pharmacol.36(17)2713-2718(1987)

 
 
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