Trifarotene (CD5789) (CD5789) 是一种有效的选择性 RARγ；激动剂。
| Cas No. | 895542-09-3 |
| 别名 | 曲法罗汀; CD5789 |
| Canonical SMILES | O=C(C1=CC=C(C2=CC=C(OCCO)C(C3=CC=C(N4CCCC4)C(C(C)(C)C)=C3)=C2)C=C1)O |
| 分子式 | C29H33NO4 |
| 分子量 | 459.58 |
| 溶解度 | DMSO: 250 mg/mL (543.97 mM) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Trifarotene is a retinoic acid receptor (RAR) agonist with Kdapp of 2, 15 and 500 nM for RARγ, RARβ and RARα, respectively. [1]. Thibaud Biadatti, et al. Novel ligands that modulate rar receptors, and use thereof in human medicine and in cosmetics. WO 2006066978 A1. |
