Meranzin是一种从传统中药Chaihu-Shugan-San(CSS)中的生物活性化合物。Meranzin从紫茉莉叶中分离出的，可以调节共有的α2-肾上腺素受体，并参与AMPA-ERK1/2-BDNF信号传导。Meranzin具有预防动脉粥样硬化和抑郁症合并症的潜力。
| Cas No. | 23971-42-8 |
| 别名 | 橙皮内酯 |
| Canonical SMILES | COC1=CC=C(C=C2)C(OC2=O)=C1C[C@H](O3)C3(C)C |
| 分子式 | C15H16O4 |
| 分子量 | 260.29 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Meranzin is an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS). Meranzin, isolated from leaves of Murraya exotica L., regulates the shared alpha 2-adrenoceptor and involves the AMPA-ERK1/2-BDNF signaling pathway. Meranzin has the potential for the prevention of the comorbidity of atherosclerosis and depression[1][2]. [1]. Lan Li, et al. Chaihu-Shugan-San and Absorbed Meranzin Hydrate Induce Anti-Atherosclerosis and Behavioral Improvements in High-Fat Diet ApoE -/- Mice via Anti-Inflammatory and BDNF-TrkB Pathway. Biomed Pharmacother. 2019 Jul;115:108893.
[2]. Rongwei Yan, et al. Preparative Isolation and Purification of Hainanmurpanin, Meranzin, and Phebalosin From Leaves of Murraya Exotica L. Using Supercritical Fluid Extraction Combined With Consecutive High-Speed Countercurrent Chromatography. J Sep Sci. 2018 May;41(9):2092-2101. |
