Atosiban acetate (RW22164 acetate;RWJ22164 acetate) 是一种九肽，竞争性的加压素/催产素受体 (vasopressin/oxytocin receptor) 拮抗剂，也是一种脱氨基催产素类似物。Atosiban acetate 是一种主要的宫缩抑制剂，可用于自发早产的研究。
| Cas No. | 914453-95-5 |
| 别名 | 醋酸阿托西班; RW22164 acetate; RWJ22164 acetate |
| Canonical SMILES | O=C([C@H](CSSCCC(N[C@@H](C1=O)CC2=CC=C(OCC)C=C2)=O)NC([C@@H](NC(C(NC([C@](N1)([H])[C@@H](C)CC)=O)[C@H](O)C)=O)CC(N)=O)=O)N(CCC3)[C@@H]3C(N[C@@H](CCCN)C(NCC(N)=O)=O)=O.OC(C)=O |
| 分子式 | C45H71N11O14S2 |
| 分子量 | 1054.24 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Atosiban acetate (RW22164 acetate;RWJ22164 acetate) is a nonapeptide competitive vasopressin/oxytocin receptor antagonist, and is a desamino-oxytocin analogue. Atosiban is the main tocolytic agent and has the potential for spontaneous preterm labor research[1]. [1]. Sanu O, et al. Critical appraisal and clinical utility of atosiban in the management of preterm labor. Ther Clin Risk Manag. 2010 Apr 26;6:191-9.
[2]. Philip J Ryan, et al. Oxytocin-receptor-expressing Neurons in the Parabrachial Nucleus Regulate Fluid Intake. Nat Neurosci. 2017 Dec;20(12):1722-1733. |
