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Berteroin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Berteroin图片
CAS NO:4430-42-6
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Berteroin,一种天然存在的萝卜硫素类似物,是一种抗转移剂。
Cas No.4430-42-6
Canonical SMILESCSCCCCCN=C=S
分子式C7H13NS2
分子量175.3
溶解度DMF: 3 mg/ml,DMSO: 16 mg/ml,Ethanol: 20 mg/ml,PBS (pH 7.2): 10 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Berteroin is a sulforaphane analog found in cruciferous vegetables including Chinese cabbage, rucola salad leaves, and mustard oil. At 1.7 µM, it has been shown to double the phase II enzyme quinone reductase activity in mouse hepatoma cells. Berteroin exerts anti-inflammatory activity in LPS-stimulated RAW 264.7 macrophages, inhibiting degradation of IκBα, as well as NF-κB p65 translocation to the nucleus and DNA binding activity. It also suppresses IRAK degradation and phosphorylation of TAK1, p38 MAPK, ERK1/2, and Akt.

 
 
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