Triptorelin是一个GnRH兴奋剂,能够抑制雌二醇引起的细胞增殖。
| Cas No. | 57773-63-4 |
| 别名 | 曲普瑞林 |
| Canonical SMILES | Pyr-His-Trp-Ser-Tyr-{d-Trp}-Leu-Arg-Pro-Gly-NH2 |
| 分子式 | C64H82N18O13 |
| 分子量 | 1311.45 |
| 溶解度 | DMF: 10mg/mL,DMSO: 3mg/mL,PBS (pH 7.2): 3mg/mL |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Triptorelin is a GnRH agaonist shown to inhibit estradiol-induced cancer cell proliferationIn vivo: (1) Triptorelin can improve the pregnancy rate by 12% to 15% in ewes6 and downregulate ovarian GnRHR-I expression of female rats, especially in late-growing follicles.(2) Triptorelin immunity blocked EET and UWT, inhibited uterine growth and development and enhance the expression levels s of ESR1, LHR, and FSHR proteins. [1]. Wei S et al. Triptorelin and cetrorelix induce immune responses and affect uterine development and expressions of genes and proteins of ESR1, LHR, and FSHR of mice. Immunopharmacol Immunotoxicol. 2016 Jun;38(3):197-204. |