Cardanol monoene (Cardanol C15:1) 是一种酚类化合物，可在腰果壳液中找到。 Cardanol monoene 可以诱导人黑色素瘤细胞中线粒体相关的细胞凋亡。
| Cas No. | 501-26-8 |
| 别名 | 腰果酚(C15:1),Cardanol C15 |
| 化学名 | 3-8Z-pentadecen-1-yl-phenol |
| Canonical SMILES | OC1=CC=CC(CCCCCCC/C=C\CCCCCC)=C1 |
| 分子式 | C21H34O |
| 分子量 | 302.5 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 15 mg/ml,Ethanol: 22 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Cardanol monoene is a phenol found in cashew nut shell liquid that reversibly inhibits tyrosinase with an IC50 value of 56 uM in vitro. It halts the cell cycle at the S phase and inhibits proliferation dose- and time-dependently in M14 melanoma cells (IC50s = 23.15 and 12.30 uM after 24 and 48 hours of treatment, respectively). Cardanol monoene also induces apoptosis via the intrinsic pathway following the accumulation of reactive oxygen species (ROS). A mixture of cardanol mono-, di-, and triene is used to synthesize cardanol-metal complexes that inhibit uropathogenic E. coli biofilm formation. |
