Diflorasone diacetate 是一种抗炎类固醇化合物，用作局部或局部药剂。
| Cas No. | 33564-31-7 |
| 别名 | 醋酸双氟拉松；二醋酸二氟拉松 |
| Canonical SMILES | F[C@]12[C@@]([C@@](C[C@H](C)[C@]3(OC(C)=O)C(COC(C)=O)=O)([H])[C@]3(C)C[C@@H]2O)([H])C[C@H](F)C4=CC(C=C[C@@]41C)=O |
| 分子式 | C26H32F2O7 |
| 分子量 | 494.5 |
| 溶解度 | Chloroform: Slightly Soluble,Methanol: Slightly Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Diflorasone is a corticosteroid with anti-inflammatory activity. It reduces production of the inflammatory cytokines Il-6, Il-4, and macrophage inflammatory protein-2 (Mip-2) and completely inhibits swelling in the ears of toluene-2,4-diisocyaniate-sensitized mice following topical administration of 20 µL of a 0.05% solution. Diflorasone inhibits RANTES and thymus and activation regulated chemokine (TARC) in a dinitrochlorobenzene-induced mouse model of allergic contact dermatitis. It also inhibits proliferation of human keratinocytes in vitro and reduces epidermal thickening in a mouse model of psoriasis induced by imiquimod . |
