ACTH 4-11(Adrenocorticotropic Hormone(4-11),human)

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CAS NO:

67224-41-3

包装与价格：

ACTH 4-11 (Adrenocorticotropic Hormone (4-11), human) 是一种促肾上腺皮质激素片段，仅在高剂量（100 和 1000 nM）下具有弱 α-促黑素细胞激素 (α-MSH) 效力。

Cas No.	67224-41-3
别名	Adrenocorticotropic Hormone (4-11), human
Canonical SMILES	Met-Glu-His-Phe-Arg-Trp-Gly-Lys
分子式	C₅₀H₇₁N₁₅O₁₁S
分子量	1090.26
溶解度	DMF: 10mg/mL,DMSO: 10mg/mL,PBS (pH 7.2): 10mg/mL
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	ACTH (4-11), an adrenocorticotropin hormone fragment, possesses a weak α-melanocyte stimulating hormone (α-MSH) potency only at high doses (100 and 1000 nM). α-melanocyte stimulating hormone (MSH) induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. Adrenocorticotropic hormone (ACTH) possesses the same amino acid sequence as MSH does. α-MSH induces the differentiation of mouse epidermal melanocytes in vivo and in vitro. ACTH (4-11) loses almost all activity for the binding to melanocortin receptor 1 (MC1R)[1]. [1]. Hirobe T, et al. ACTH(4-12) is the minimal message sequence required to induce the differentiation of mouse epidermal melanocytes in serum-free primary culture. J Exp Zool. 2000 May 1;286(6):632-40.