3-Demethylcolchicine 是秋水仙碱的代谢产物，碳环上有一个羟基参与自由基的清除并且能显著抑制角叉菜胶水肿。
| Cas No. | 7336-33-6 |
| 别名 | 3-去甲秋水仙碱 |
| 分子式 | C21H23NO6 |
| 分子量 | 385.41 |
| 溶解度 | DMSO : 100 mg/mL (259.46 mM; Need ultrasonic) |
| 储存条件 | 4°C, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Demethylcolchicine, a colchicine metabolite, possesses a hydroxy-group on its carbon ring that could participate in radical scavenging and markedly inhibits the carrageenin edema[1][2]. [1]. Modriansky M, et al. Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants•. Toxicology. 2002;177(1):105-117.
[2]. Sugio K, et al. Separation of tubulin-binding and anti-inflammatory activity in colchicine analogs and congeners. Life Sci. 1987;40(1):35-39. |
