8-Gingerol来源于姜的根状茎(Z.officinale)，具有口服活性，可激活TRPV1，EC50值为5.0µM。8-Gingerol抑制COX-2，还能抑制体外H.pylori的生长。
| Cas No. | 23513-08-8 |
| 别名 | 8-姜辣醇 |
| Canonical SMILES | CCCCCCC[C@H](O)CC(CCC1=CC=C(O)C(OC)=C1)=O |
| 分子式 | C19H30O4 |
| 分子量 | 322.44 |
| 溶解度 | DMSO: ≥ 100 mg/mL (310.14 mM) |
| 储存条件 | Store at -20°C, sealed storage, away from moisture and light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 8-Gingerol, found in the rhizomes of ginger (Z. officinale) with oral bioavailability, activates TRPV1, with an EC50 of 5.0 µM. 8-Gingerol inhibits COX-2, and inhibits the growth of H. pylori in vitro[1][2]. [1]. Dedov, V.N., et al. Gingerols: a novel class of vanilloid receptor (VR1) agonists. Br. J. Pharmacol. 137(6), 793-798 (2002).
[2]. Chrubasik, S., et al. Zingiberis rhizoma: A comprehensive review on the ginger effect and efficacy profiles. Phytomedicine 12(9), 684-701 (2005). |
