| CAS NO: | 131926-98-2 |
| 包装: | 1mg |
| 市场价: | 1260元 |
| Cas No. | 131926-98-2 |
| 别名 | 5-羟基兰索拉唑,AG1908 |
| Canonical SMILES | OC1=CC=C2N=C(NC2=C1)S(CC3=NC=CC(OCC(F)(F)F)=C3C)=O |
| 分子式 | C16H14F3N3O3S |
| 分子量 | 385.36 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 5-Hydroxylansoprazole (AG1908) is an active metabolite of Lansoprazole in plasma. Lansoprazole is metabolized by CYP2C19 forming 5-Hydroxylansoprazole. Lansoprazole is a gastric proton-pump inhibitor and is effective in the treatment of various peptic diseases[1][2]. [1]. Xu HR, et al. The effect of CYP2C19 activity on pharmacokinetics of lansoprazole and its active metabolites in healthy subjects. Pharm Biol. 2010 Aug;48(8):947-52. doi: 10.3109/13880200903300220. [2]. KatarÍna KostolanskÁ, et al. Determination of lansoprazole, 5-hydroxylansoprazole, and lansoprazole sulfone in human plasma for CYP2C19 and CYP3A4 phenotyping. Chemical Papers. volume 73, pages2955-2963(2019). |
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