Fipronil 是一种杀虫剂，可作为昆虫 GABA 受体的选择性拮抗剂（蟑螂和大鼠受体的 IC50s = 30 nM 和 1,600 nM）。
| Cas No. | 120068-37-3 |
| 别名 | 氟虫腈 |
| Canonical SMILES | N#CC1=NN(C2=C(Cl)C=C(C(F)(F)F)C=C2Cl)C(N)=C1S(C(F)(F)F)=O |
| 分子式 | C12H4Cl2F6N4OS |
| 分子量 | 437.15 |
| 溶解度 | DMSO: 250 mg/mL (571.89 mM) |
| 储存条件 | 4℃, protect from light, stored under nitrogen |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Fipronil is an insecticide that acts as a selective antagonist of insect GABA receptors (IC50s = 30 nM and 1,600 nM for cockroach and rat receptors, respectively). Fipronil also inhibits desensitizing and non-desensitizing glutamate-induced chloride currents in cockroach neurons (IC500s = 800 nM and 10 nM, respectively). Fipronil induces activity of the cytochrome P450 (CYP) isoforms CYP1A1/2, CYP2B1/2, and CYP3A1/2 in isolated rat liver microsomes. |
