Aminoethyl-SS-ethylalcohol 是一种谷胱甘肽可降解 (cleavable) 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
Cas No. | 15579-01-8 |
分子式 | C4H11NOS2 |
分子量 | 153.27 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Aminoethyl-SS-ethylalcohol is a glutathione cleavableADC linkerused in the synthesis of antibody-drug conjugates (ADCs)[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].
[1]. Yuelog Ma, et al. HUMANIZED LEWIS-Y SPECIFIC ANTIBODY-BASED DELIVERY OF DICER SUBSTRATE siRNA (D-siRNA) AGAINST STAT3. US20130052731A1. |