CAS NO: | 1092554-87-4 |
包装: | 1g |
市场价: | 6826元 |
Cas No. | 1092554-87-4 |
分子式 | C22H38O9 |
分子量 | 446.53 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Bis-propargyl-PEG8 (compound 16e) is a PEG-basedPROTAC linkercan be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Jervis PJ, et al. Towards multivalent CD1d ligands: synthesis and biological activity of homodimeric α-galactosyl ceramide analogues. Carbohydr Res. 2012 Jul 15;356:152-62. |
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