Cas No. | 99365-40-9 |
别名 | 6-溴-1,3-二氢-2H-吲哚-2-酮 |
Canonical SMILES | BrC1=CC=C(CC(N2)=O)C2=C1 |
分子式 | C8H6BrNO |
分子量 | 212 |
溶解度 | DMF: 10 mg/ml,DMSO: 3 mg/ml,Ethanol: 10 mg/ml,Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 6-Bromo-2-oxindole is a secondary metabolite that has been isolated from the sea squirt (D. skoogi). It is cytotoxic to MDA-MB-231 breast cancer cells with an IC50 value of 74.41 µM. 6-Bromo-2-oxindole has been used in the synthesis of 1,3-disubstituted 2-oxindoles and indolin-2-one p38α inhibitors, which have anti-inflammatory activity. |