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Acetylcorynoline
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Acetylcorynoline图片
CAS NO:18797-80-3
包装:20mg
市场价:1838元

Acetylcorynoline 是从延胡索中提取的主要生物碱成分，具有抗炎特性。
Cas No.18797-80-3
别名乙酰紫堇灵
化学名(5bR,6S,12bR)-5b,13-dimethyl-5b,6,7,12b,13,14-hexahydro-[1,3]dioxolo[4',5':4,5]benzo[1,2-c][1,3]dioxolo[4,5-i]phenanthridin-6-yl acetate
Canonical SMILESO=C(C([H])([H])[H])O[C@](C([H])([H])C1=C2[H])([H])[C@@]3(C([H])([H])[H])[C@](C1=C([H])C4=C2OC([H])([H])O4)([H])N(C([H])([H])[H])C([H])([H])C5=C3C([H])=C([H])C6=C5OC([H])([H])O6
分子式C23H23NO6
分子量409.43
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Acetylcorynoline is the major alkaloid component derived from Corydalis bungeana, and has anti-inflammatory properties[1].

Acetylcorynoline significantly inhibits the secretion of tumor necrosis factor-α, interleukin-6, and interleukin-12p70 by LPS-stimulated Dendritic cells (DCs)[1].Acetylcorynoline significantly inhibits LPS-induced activation of IκB kinase and mitogen-activated protein kinase[1].

References:
[1]. Fu RH, et al. Acetylcorynoline attenuates dopaminergic neuron degeneration and α-synuclein aggregation in animal models of Parkinson's disease. Neuropharmacology. 2014 Jul;82:108-20.

 
 
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