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FABP5-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
FABP5-IN-1图片
CAS NO:2132990-98-6
包装与价格:
包装价格(元)
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FABP5-IN-1 是一种选择性,高亲和力脂肪酸结合蛋白 5 (FABP5) 抑制剂,Ki 值为 1.7 μM。FABP5-IN-1 与 FABP3 和 FABP7 均不结合,并具有有效的镇痛作用。
Cas No.2132990-98-6
分子式C34H30O6
分子量534.6
溶解度DMSO : 125 mg/mL (233.82 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

FABP5-IN-1 is a selective and high affinity fatty acid binding protein 5 (FABP5) inhibitor with a Ki value of 1.7 μM, and does not bind to both FABP3 and FABP7. FABP5-IN-1 shows potent antinociceptive effects[1].

FABP5-IN-1 (Compounds 4j; 20 mg/kg; intraperitoneal injection; for 90 minutes; male wild-type C57BL/6 mice) treatment displays potent antinociceptive effects in CFA model[1].

[1]. Yan S, et al. SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins. Eur J Med Chem. 2018 Jun 25;154:233-252.

 
 
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