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3-O-Methylgallic acid
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
3-O-Methylgallic acid图片
CAS NO:3934-84-7
包装:500mg
市场价:450元

3-O-Methylgallicacid(3,4-Dihydroxy-5-methoxybenzoicacid)是一种花青素代谢产物，具有强大的抗氧化能力。3-O-Methylgallicacid能抑制Caco-2细胞增殖，IC50值为24.1μM。3-O-Methylgallicacid还诱导细胞凋亡(apoptosis)并具有抗癌作用。
Cas No.3934-84-7
别名3-O-甲基没食子酸,3,4-Dihydroxy-5-methoxybenzoic acid
Canonical SMILESO=C(O)C1=CC(OC)=C(O)C(O)=C1
分子式C8H8O5
分子量184.15
溶解度DMSO: 50 mg/mL (271.52 mM); Water: 2.2 mg/mL (11.95 mM)
储存条件Store at -20℃
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

3-O-Methylgallic acid (3,4-Dihydroxy-5-methoxybenzoic acid) is an anthocyanin metabolite and has potent antioxidant capacity. 3-O-methylgallic acid inhibits Caco-2 cell proliferation with an IC50 value of 24.1 μM. 3-O-methylgallic acid also induces cell apoptosis and has anti-cancer effects[1][2].

[1]. Forester SC, et al. Gut metabolites of anthocyanins, gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde, inhibit cell proliferation of Caco-2 cells. J Agric Food Chem. 2010 May 12;58(9):5320-7. [2]. Forester SC, The anthocyanin metabolites gallic acid, 3-O-methylgallic acid, and 2,4,6-trihydroxybenzaldehyde decrease human colon cancer cell viability by regulating pro-oncogenic signals. Mol Carcinog. 2014 Jun;53(6):432-9.

 
 
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