Sirt2-IN-1(Compound9)是一种sirtuin2(Sirt2)抑制剂，IC50为163nM。
| Cas No. | 1862238-00-3 |
| Canonical SMILES | O=C(NC1=NC=C(CC2=CC=CC(OCC3=CN(CC4=CC=CC=C4)N=N3)=C2)S1)CSC5=NC(C)=CC(C)=N5 |
| 分子式 | C28H27N7O2S2 |
| 分子量 | 557.69 |
| 溶解度 | DMSO : 150 mg/mL (268.97 mM);Water :< 0.1 mg/mL (insoluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Sirt2-IN-1 (Compound 9) is a sirtuin 2 (Sirt2) inhibitor with an IC50 of 163 nM[1].
SIRT2|163 nM (IC50) [1]. Schiedel M, et al. Structure-Based Development of an Affinity Probe for Sirtuin 2. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6. |
