1-Palmitoyl-2-hydroxy-sn-glycero-3-PC 是一种丰富的性腺 LPC（溶血磷脂酰胆碱）。
| Cas No. | 17364-16-8 |
| 别名 | 1-十六酰-SN-丙三醇-磷酸胆碱 |
| Canonical SMILES | CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)COP(=O)(O)OCC[N](C)(C)C |
| 分子式 | C24H50NO7P |
| 分子量 | 495.6 |
| 溶解度 | PBS (pH 7.2): 2 mg/ml |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC is the ubiquitous lipid species generated following phospholipase A2 (PLA2) hydrolysis of phosphatidylcholine. The hydrolysis of phospholipids by arachidonoyl-selective PLA2s is the initiating event in many eicosanoid-based signal transduction pathways. Many other reactions also generate phosphatidylcholine species with a free hydroxyl group in the sn-2 position. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC augments inflammation through effects on adhesion molecules and growth factors, monocytes, and macrophages. The lymphocyte G protein-coupled receptor G2A binds 1-palmitoyl-2-hydroxy-sn-glycero-3-PC as a specific ligand with a Kd of 65 nM; this receptor also binds the related phospholipid sphingosyl phosphorylcholine. |
