Seco-Duocarmycin SA 是一种高效的 DNA 烷化剂 (DNA alkylator),可作用做抗体-药物偶联物 (ADC) 的毒素部分。
Cas No. | 144667-38-9 |
Canonical SMILES | O=C(C1=CC2=C3C(N(C(C(N4)=CC5=C4C(OC)=C(OC)C(OC)=C5)=O)CC3CCl)=CC(O)=C2N1)OC |
分子式 | C25H24ClN3O7 |
分子量 | 513.93 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Seco-Duocarmycin SA is a highly potent DNA alkylator, and is used as an ADC cytotoxin[1]. [1]. Lutz F. Tietze, et al. A Concise and Efficient Synthesis of seco-Duocarmycin SA. European Journal of Organic Chemistry 2003 (3), 562-566. |