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CBS1117
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CBS1117图片
CAS NO:959245-08-0
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CBS1117 抑制病毒进入,对甲型流感病毒 A/Puerto Rico/8/34 (H1N1) 的 IC50 为 70 nM。CBS1117 干扰血凝素 (HA) 介导的融合过程。
Cas No.959245-08-0
分子式C15H20Cl2N2O
分子量315.24
溶解度DMSO : 250 mg/mL (793.05 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

CBS1117 is a virus entry inhibitor with an IC50 of 70 nM for influenza A virus, A/Puerto Rico/8/34 (H1N1). CBS1117 interferes with the hemagglutinin (HA)-mediated fusion process[1].

CBS1117 has a lower IC50 value of 70 nM and higher CC50 value of 274 μM, leading to an excellent antiviral selectivity index value (SI value of 3914) in human lung epithelial cell line (A549)[1].

[1]. Hussein AFA, et al. Identification of entry inhibitors with 4-aminopiperidine scaffold targeting group 1 influenza A virus. Antiviral Res. 2020 May;177:104782.

 
 
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