Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 是基质金属蛋白酶 14 (MMP-14) 的荧光底物。
Cas No. | 1926163-82-7 |
Canonical SMILES | COC1=CC=C2C(OC(C=C2CC(N3[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CNC4=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C4)=O)=O)C)=O)CC5=CNC6=C5C=CC=C6)=O)CSCC7=CC=C(OC)C=C7)=O)C)=O)=O)CCC3)=O)=O)=C1 |
分子式 | C66H82N16O17S |
分子量 | 1403.5 |
溶解度 | Formic Acid: 1 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Mca-PLAC(p-OMeBz)-WAR(Dpa)-NH2 is a fluorogenic substrate for matrix metalloproteinase-14 (MMP-14). Upon cleavage by MMP-14, 7-methoxycoumarin-4-acetyl (Mca) is released and its fluorescence can be used to quantify MMP activity. Mca displays excitation/emission maxima of 328/420 nm, respectively. |